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Keith Diaz, PhD

  • Associate Research Scientist

Dr. Keith Diaz oversees the Exercise Testing Laboratory at the Center for Behavioral Cardiovascular Health. His research focuses on the role of prolonged sedentary behavior in the pathogenesis of cardiovascular disease, with a specific focus of iteratively optimizing feasible, sustainable, and cost-effective guidelines for reducing prolonged sitting. His current work involves examining the biological mechanisms through which cardiorespiratory fitness buffers and sedentary behavior augments the deleterious cardiovascular consequences of negative emotions. This laboratory-based study tests the hypothesis that negative mood-induced endothelial dysfunction is attenuated with higher cardiorespiratory fitness and is augmented with prolonged sedentary behavior. Dr. Diaz is also interested in the objective measurement of physical activity and sedentary behavior via accelerometry. He has conducted a laboratory-based study testing the validity and reliability of wireless physical activity monitors including the Fitbit One and Fitbit Flex. Dr. Diaz’s past work has involved studying the effects of aerobic exercise training on endothelial health in sedentary African Americans. Findings from this work included the observation that aerobic exercise training elicited robust reductions in circulating endothelial microparticles; the first study to demonstrate a favorable effect of a lifestyle intervention on circulating endothelial microparticles.

Departments And Divisions

  • Department of Medicine

Education & Training

  • BS, 2006 Exercise Physiology, William Paterson University
  • PhD, 2012 Exercise Science, Temple University

Lab Locations

  • Presbyterian Hospital Building (PH)

    622 West 168th Street
    PH 9, Room 319
    New York, NY 10032
    Phone:
    (212) 304-5231
    Email:
    kd2442@cumc.columbia.edu

NIH Grants

  • IMPACT OF PROLONGED SEDENTARY BEHAVIOR ON CARDIAC OUTCOMES AND MORTALITY IN ACUTE CORONARY SYNDROME PATIENTS (Federal Gov)

    Jan 1 2017 - Dec 31 2020

    MIDCAREER INVESTIGATOR AWARD IN PATIENT-ORIENTED RESEARCH IN HUMAN HYPERTENSION (Federal Gov)

    Feb 1 2015 - Jan 31 2020

    TESTING BIOPSYCHOSOCIAL MECHANISMS OF THE POSTHOSPITAL SYNDROME MODEL OFEARLY REHOSPITALIZATION IN ACUTE CORONARY SYNDROME PATIENTS (Federal Gov)

    Jan 1 2016 - Dec 31 2019

    TEST OF A NEW THEORY TO EXPLAIN EXCESS RISK IN CARDIAC PTSD (Federal Gov)

    Jul 15 2015 - Mar 31 2019

    EXERCISE, AGE-RELATED MEMORY DECLINE, AND HIPPOCAMPAL FUNCTION (Federal Gov)

    Sep 15 2010 - May 31 2017

    EXERCISE, AGING, AND COGNITION: EFFECT AND MECHANISMS (Federal Gov)

    Aug 1 2010 - May 31 2017

    PSYCHOSOCIAL FACTORS AND CARDIOVASCULAR DISEASE (Federal Gov)

    Sep 1 1994 - Feb 28 2017

    MIDCAREER MENTORING IN BEHAVIORAL CARDIOLOGY: DEPRESSSION & CARDIOVASCULAR (Federal Gov)

    Sep 1 2006 - Jul 31 2016

    INCORPORATION OF A HYPERTENSION WORKING GROUP INTO THE JACKSON HEART STUDY (Federal Gov)

    Jul 15 2013 - Jun 30 2016

    EXERCISE AND INFLAMMATION: AUTONOMIC, AFFECTIVE & CELLULAR MECHANISMS (Federal Gov)

    Sep 15 2009 - May 31 2015

    PHYSICAL ACTIVITY, DEPRESSION, AND POST-ACS (Federal Gov)

    Sep 1 2009 - Jun 30 2014

Publications

  • Diaz KM, Krupka DJ, Chang MJ, Peacock J, Ma Y, Goldsmith J, Schwartz JE, Davidson KW. Fitbit: An accurate and reliable device for wireless physical activity tracking. Int J Cardiol. 2015; 2015;185:138-140. PMCID: PMC4406840 [Available on 2016-04-15]
  • Diaz KM, Tanner RM, Falzon L, Levitan EB, Reynolds K, Shimbo D, Muntner P. Visit-to-visit variability of blood pressure and cardiovascular disease and all-cause mortality: a systematic review and meta-analysis. Hypertension, 2014;64(5):965-982. PMCID: PMC4217251
  • Diaz KM, Booth JN III, Calhoun DA, Irvin MR, Howard G, Safford MM, Muntner P, Shimbo D. Healthy lifestyle factors and risk of cardiovascular events and mortality in treatment-resistant hypertension: the Reasons for Geographic and Racial Differences in Stroke study. Hypertension. 2014;64(3):465-471. PMCID: PMC4134352
  • Feairheller DL, Diaz KM, Kashem MA, Thakkar SR, Veerabhadrappa P, Strugeon KS, Ling C, Williamson ST, Kretzschmar J, Lee H, Grimm H, Babbitt DM, Vin C, Fan X, Crabbe DL, Brown MD. Effects of moderate aerobic exercise training on vascular health and blood pressure in African Americans. J Clin Hypertens (Greenwich). 2014;16(7):504-510. PMCID: PMC4107013
  • Diaz KM, Muntner P, Levitan EB, Brown MD, Babbitt DM, Shimbo D. The effects of weight loss and salt reduction on visit-to-visit blood pressure variability: results from a multicenter randomized controlled trial. J Hypertens. 2014;32(4):840-848. PMCID: PMC4024203
  • Kretzschmar J, Babbitt DM, Diaz KM, Feairheller DL, Sturgeon KM, Perkins A, Veerabhadrappa P, Williamson ST, Ling C, Lee H, Grimm H, Thakkar SR, Crabbe DL, Kashem MA, Brown MD. A standardized exercise intervention differentially affects pre- and post-menopausal African American women. Menopause. 2014;21(6):579-584. PMCID: PMC4013263
  • Diaz KM, Shimbo D. Physical activity and the prevention of hypertension. Curr Hypertens Rep. 2013;15(6):659-668. PMCID: PMC3901083
  • Babbitt DM, Diaz KM, Feairheller DL, Sturgeon KM, Perkins AM, Veerabhadrappa P, Williamson ST, Kretzschmar J, Ling C, Lee H, Grimm H, Thakkar SR, Crabbe DL, Kashem MA, Brown MD. Endothelial activation microparticles and inflammation status improve with exercise training in African Americans. Int J Hypertens. 2013;2013:538017. PMCID: PMC3652180.
  • Diaz KM, Feairheller DL, Sturgeon KM, Williamson ST, Brown MD. Oxidative stress response to short duration bout of submaximal aerobic exercise in healthy young adults. Int J Exerc Sci. 2011;4(4): 247-256. PMCID: PMC3856905
  • Feairheller DL, Diaz KM, Sturgeon KM, Williamson S, Brown MD. Racial differences in the time-course oxidative stress responses to acute exercise. J Exerc Physiol. 2011;14(1):49-59. PMCID: PMC3118095