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Current Research Projects

  • PI: D. Edmondson
    R01 HL117832; 2013-2018; $3,155,309
    NIH/NHLBI: Impact of Social-Interpersonal Factors in the ER on PTSD/Cardiac Outcomes
    The goal of this study is to identify modifiable emergency department and interpersonal factors associated with poor medical and psychological prognosis in ACS patients.
  • PI: D. Shimbo
    K24 HL125704; 2015-2020; $3,458,334
    NIH/NHLBI: Midcareer Investigator Award in Patient-Oriented Research in Human Hypertension
    The overall goals of this program are to investigate the behavioral, psychosocial and biological processes in the pathogenesis of human hypertension, as well as train the next generation of scientists in hypertension research.
  • PI: K. Davidson
    SC14-1403-12304; 2014-2017; $1,049,741
    PCORI: Engaging Stakeholders in Building Patient-centered, N-of-1 Randomized and Other
    The aims of this research are to conduct focus groups and then a large, national survey of patients to better understand the settings in which N-of-1 randomized control trial (NCT) are most needed for patients, the barriers and facilitators to their conduct. As well as, create educational materials to inform patients of the pros and cons of these trials, and determine which directions these methods should take to be most useful to patients.
  • PI: K. Davidson
    R01 HL114924; 2013-2018; $3,819,703
    NIH/NHLBI: Depression Screening RCT in ACS patients: Quality of Life and Cost Outcomes
    The goal of this study is to examine in a randomized controlled trial the benefits and costs of the American Heart Association’s advisory for depression screening and treatment of post-ACS patients.
  • PI: D. Shimbo
    R01 HL116470; 2013-2018; $629,503
    NIH/NHLBI: Translational Research of Negative Emotions and Acute Endothelial Dysfunction
    The aims of this study are to primarily examine the acute effects of provoked anger and secondarily depressed mood and anxiety on endothelial cell health.
    • Supplement PI: K. Diaz 2014 - 2018 $452,002
      The primary aims of this study are to examine whether the harmful effects of negative mood on blood vessel health can be buffered by higher levels of cardiorespiratory fitness and daily physical activity.
    • Supplement PI: D. Mota 2015-2018 $70,644
      The aims of this study are to primarily examine the acute effects of provoked anger and secondarily depressed mood and anxiety on endothelial cell health. A laboratory-based, randomized controlled experiment is used to test whether provoked anger, depressed mood and anxiety will induce endothelial dysfunction in humans.
  • PI: I. Kronish
    R01 HL123368; 2014-2018; $1,835,510
    NIH/NHLBI: PTSD, Medication Adherence, and Prognosis after Acute Coronary Syndromes
    The goal of this ancillary study is to identify a target for intervention after an acute coronary syndrome (ACS) that may decrease risk for recurrent cardiac events and mortality among patients who develop posttraumatic stress disorder (PTSD) due to the ACS.
  • PI: W. Whang
    R01 HL128310; 2015-2019; $2,604,529
    NIH/NHLBI: Test of a new theory to explain excess risk in cardiac PTSD
    This study tests a new theory to explain the excess risk associated with posttraumatic stress disorder (PTSD) due to non ST-elevation myocardial infarction and unstable angina; the two most common forms of acute coronary syndrome.
  • PI: I. Kronish

    R01 HS024262-05; 2015-2020; $1,249,449                                                                                                                      AHRQ: Increasing the Uptake of the USPSTF Hypertension Screening Guidelines in Primary Care                The goal of this proposal is to determine the optimal approach to implementing the recent draft update to the U.S. Preventive Services Task Force (USPSTF) guidelines for hypertension screening in underserved primary care settings.

  • PI: K. Davidson                                                                                                                                                               U24 AG052175-02; 2015-2020; $7,098,340                                                                                                                NIH/NIA: Columbia University Science of Behavior Change Resource and Coordinating Center

    • Supplement. PI: K Davidson 2016-2017 $80,000                                                                                                 NIH/NIA: Columbia University Science of Behavior Change Resource and Coordinating Center: Open Science Administrative Supplement.

  • PI: D. Edmondson

    R01-HL128497-01A1: 2016-2019; $3,017,339                                                                                                NIH/NHLBI: Testing biopsychosocial mechanisms of the posthospital syndrome model of early                      rehospitalization in acute coronary syndrome patients                                                                                               A new model of “posthospital syndrome” suggests that the stress of hospitalization itself confers increased risk of rehospitalization because it places patients in a transient state of generalized risk. The aim of this study is to test this model, and identify hospital environment and patient factors that place patients at risk.

  • PI: D.Edmondson                                                                                                                                                               R01-HL132347-01; 2016-2020; $3,091,668                                                                                                          NIH/NHLBI: Impact of PTSD on cardiovascular risk in survivors of stroke and transient ischemic attack                                  

  • PI: J. Sumner                                                                                                                                                                      K01-HL130650-01; 2015-2020; $820,340                                                                                                                          NHLBI: Posttraumatic Stress and Cardiovascular Risk in Women: Tests of Biological Mechanisms

  • PI: K. Diaz                                                                                                                                                                       R01-HL134985-01; 2017-2020; $2,687,358                                                                                                    NIH/NHLBI: Impact of Prolonged Sedentary Behavior on Cardiac Outcomes and Mortality in Acute Coronary Syndrome Patients                                                                                                                                       The goal of this ancillary project is to evaluate prolonged sedentary behavior as a potential therapeutic target for intervention after an acute coronary syndrome (ACS; myocardial infarction or unstable angina).

  • PI: L. Wasson                                                                                                                                                                     K08; 2016-2021; $752,101                                                                                                                                                 AHRQ: Using Health Information Technology to Improve Diagnosis of Cardiovascular Disease in the        Emergency Department                                                                                                                                                   The specific objective of this proposal is to develop a health information technology tool-based intervention to improve diagnosis of ACS in the “paradigmatic complex system”15 of the adult emergency department at New York-Presbyterian Hospital – Columbia University, using the framework of cognitive hygiene.