Akiko Maehara, MD, MBA

  • Professor of Medicine at CUMC

Overview

Academic Appointments

  • Professor of Medicine at CUMC

Languages

  • Japanese

Gender

  • Female

Credentials & Experience

Education & Training

  • MD, 1993 Yamaguchi University School of Medicine, Yamaguchi, Japan
  • MBA, 2003 Business Breakthrough University, Tokyo, Japan
  • Residency: 1995 Department of Medicine, Toranomon Hospital, Tokyo, Japan
  • Fellowship: 1998 Department of Cariology, Toranomon Hospital, Tokyo, Japan
  • Fellowship: 2000 Center for Research in Cardiovascular Interventions, Stanford University, Stanford, CA
  • Fellowship: 2001 Department of Cariology, Washington Hospital Center, Washington, DC
  • Fellowship: 2002 Department of Radiology, National Cardiovascular Center, Osaka, Japan

Committees, Societies, Councils

  • American College of Cardiology, FACC 08/2017 to present
  • Society for Cardiovascular Angiography & Interventions, FSCAI 08/2020 to present
  • Society of Cardiovascular Magnetic Resonance, 2003 to present
  • Society of Cardiovascular Computed Tomography, 10/2018 to present
  • Japanese Society of Internal Medicine, 1994 to present
  • Japanese Circulation Society, 1996 to present

Editorial Boards

Editorial Board

  • Coronary Artery Disease, 09/2016 to 06/2018
  • Cardiovascular Revascularization Medicine, 01/2015 to present

Associate Editor

  • Coronary Artery Disease 07/2018 to present

Journal Reviewer

  • Arteriosclerosis Thrombosis, and Vascular Biology
  • Atherosclerosis
  • American Heart Journal
  • American Journal of Cardiology
  • Cardiovascular Revascularization Medicine
  • Catheterization and Cardiovascular Interventions
  • Circulation
  • Circulation Cardiovascular Imaging
  • Circulation Cardiovascular Interventions
  • Circulation Journal
  • Coronary Artery Disease
  • EuroIntervention
  • European Heart Journal
  • European Heart Journal Imaging
  • Heart
  • Heart and Vessels
  • International Journal of Cardiovascular Imaging
  • Journal of American College of Cardiology
  • Journal of American College of Cardiology Cardiovascular Imaging
  • Journal of American College of Cardiology Cardiovascular Interventions
  • JAMA Cardiology
  • Journal of Invasive Cardiology
  • The Lancet
  • Thrombosis Research

Honors & Awards

  • 1999: Katherine D. McCormick Award from Stanford University

Research

Selected Publications

  1. 1. Matsumura M, Mintz GS, Dohi T, Li W, Shang A, Fall K, Sato T, Sugizaki Y, Chatzizisis YS, Moses JW, Kirtane AJ, Sakamoto H, Daida H, Minamino T, Maehara A. Accuracy of IVUS-based machine learning segmentation assessment of coronary artery dimensions and balloon sizing. JACC ADVANCES 2023; 2: 100564.
  2. 2. Gogia S, Vahl TP, Thourani VH, Yadav PK, George I, Kodali SK, Hamid N, Ranard L, Chen T, Matsumura M, Maehara A, Treede H, Baldus S, Daniels D, Sheridan BC, Zahr F, Russo MJ, McCabe JM, Chetcuti SJ, Leon MB, Makkar RR, Khalique OK. Cardiac Computed Tomography Angiography Anatomical Characterization of Patients Screened for a Dedicated Transfemoral Transcatheter Valve System for Primary Aortic Regurgitation. Struct Heart. 2023;7:100164. doi: 10.1016/j.shj.2023.100164.
  3. 3. Yamamoto K, Sato T, Salem H, Matsumura M, Fall KN, Prasad M, Ng VG, Sethi SS, Nazif TM, Parikh SA, Vahl TP, Ali ZA, Karmpaliotis D, Rabbani LE, Collins MB, Leon MB, McEntegart MB, Moses JW, Kirtane AJ, Mintz GS, Maehara A. Mechanisms and treatment outcomes of ostial right coronary artery in-stent restenosis. EuroIntervention. 2023;19:e383-e393. doi: 10.4244/EIJ-D-23-00107.
  4. 4. Sato T, Yamamoto K, Matsumura M, Shlofmitz E, Khalique OK, Mintz GS, Shlofmitz RA, Jeremias A, Ali ZA, Maehara A. Discrimination of Calcified Nodule as a Cause of Coronary Angiographic Radiolucent Mass. JACC Cardiovasc Interv. 2023;16:1948-1949. 5
  5. 5. Huang M, Maehara A, Tang D, Zhu J, Wang L, Lv R, Zhu Y, Zhang X, Matsumura M, Chen L, Ma G, Mintz GS. Comparison of multilayer and single-layer coronary plaque models on stress/strain calculations based on optical coherence tomography images. Front Physiol. 2023;14:1251401. doi: 10.3389/fphys.2023.1251401.
  6. 6. Ali ZA, Landmesser U, Maehara A, Matsumura M, Shlofmitz RA, Guagliumi G, Price MJ, Hill JM, Akasaka T, Prati F, Bezerra HG, Wijns W, Leistner D, Canova P, Alfonso F, Fabbiocchi F, Dogan O, McGreevy RJ, McNutt RW, Nie H, Buccola J, West NEJ, Stone GW; ILUMIEN IV Investigators. Optical Coherence Tomography-Guided versus AngiographyGuided PCI. N Engl J Med. 2023;389:1466-1476. doi: 10.1056/NEJMoa2305861.
  7. 7. Shin D, Dai N, Wilburn P, Choi KH, Lee SH, Kim HK, Maehara A, Stone GW, Myung Lee J.Effect of Supersaturated Oxygen Therapy on Coronary Microcirculatory Function in Patients With Anterior STEMI. JACC Cardiovasc Interv. 2023;16:2469-2471. doi: 10.1016/j.jcin.2023.08.001
  8. 8. Jonas M, Genereux P, Maehara A, Ben-Yehuda O, Stone GW, Chernin G. Control of diabetes mellitus and the risk of neointimal hyperplasia after percutaneous coronary intervention: Post-hoc analysis from the BLADE-PCI trial. Atherosclerosis. 2023 doi: 10.1016/j.atherosclerosis.2023.117264.
  9. 9. Ali ZA, Kereiakes DJ, Hill JM, Saito S, Di Mario C, Honton B, Gonzalo N, Riley RF, Maehara A, Matsumura M, Shin D, Stone GW, Shlofmitz RA. Impact of Calcium Eccentricity on the Safety and Effectiveness of Coronary Intravascular Lithotripsy: Pooled Analysis From the Disrupt CAD Studies. Circ Cardiovasc Interv. 2023;16:e012898. doi: 10.1161/CIRCINTERVENTIONS.123.012898.
  10. 10. Sato T, Matsumura M, Yamamoto K, Shlofmitz E, Moses JW, Khalique OK, Thomas SV, Tsoulios A, Cohen DJ, Mintz GS, Shlofmitz RA, Jeremias A, Ali ZA, Maehara A. Impact of Eruptive vs Noneruptive Calcified Nodule Morphology on Acute and Long-Term Outcomes After Stenting. JACC Cardiovasc Interv. 2023;16:1024-1035.
  11. 11. Gu SZ, Huang Y, Costopoulos C, Jessney B, Bourantas C, Teng Z, Losdat S, Maehara A, Räber L, Stone GW, Bennett MR. Heterogeneous plaque-lumen geometry is associated with major adverse cardiovascular events. Eur Heart J Open. 2023; doi: 10.1093/ehjopen/oead038.
  12. 12. Ali ZA, Kereiakes D, Hill J, Saito S, Di Mario C, Honton B, Gonzalo N, Riley R, Maehara A, Matsumura M, Stone GW, Shlofmitz R. Safety and Effectiveness of Coronary Intravascular Lithotripsy for Treatment of Calcified Nodules. JACC Cardiovasc Interv. 2023;16:1122-1124.
  13. 13. Lv R, Wang L, Maehara A, Matsumura M, Guo X, Samady H, Giddens DP, Zheng J, Mintz GS, Tang D. Combining IVUS + OCT Data, Biomechanical Models and Machine Learning Method for Accurate Coronary Plaque Morphology Quantification and Cap Thickness and Stress/Strain Index Predictions. J Funct Biomater. 2023;14:41.
  14. 14. Gyldenkerne C, Maeng M, Kjøller-Hansen L, Maehara A, Zhou Z, Ben-Yehuda O, Erik Bøtker H, Engstrøm T, Matsumura M, Mintz GS, Fröbert O, Persson J, Wiseth R, Larsen AI, Jensen LO, Nordrehaug JE, Bleie Ø, Omerovic E, Held C, James SK, Ali ZA, Rosen HC, Stone GW, Erlinge D. Coronary Artery Lesion Lipid Content and Plaque Burden in Diabetic and Nondiabetic Patients: PROSPECT II. Circulation. 2023;147:469-481.
  15. 15. Huang M, Maehara A, Tang D, Zhu J, Wang L, Lv R, Zhu Y, Zhang X, Matsumura M, Chen L, Ma G, Mintz GS. Human Coronary Plaque Optical Coherence Tomography Image Repairing, Multilayer Segmentation and Impact on Plaque Stress/Strain Calculations. J Funct Biomater. 2022;13:213.
  16. 16. Seike F, Mintz GS, Matsumura M, Ali ZA, Liu M, Jeremias A, Ben-Yehuda O, De Bruyne B, Serruys PW, Yasuda K, Stone GW, Maehara A. Impact of Intravascular Ultrasound-Derived Lesion-Specific Virtual Fractional Flow Reserve Predicts 3- Year Outcomes of Untreated Nonculprit Lesions: The PROSPECT Study. Circ Cardiovasc Interv. 2022;15:851-860.
  17. 17. Noguchi M, Gkargkoulas F, Matsumura M, Kotinkaduwa LN, Hu X, Usui E, Fujimura T, Seike F, Salem H, Jin G, Li C, Yamamoto K, Sato T, Redfors B, Fall KN, Nazif TM, Ali ZA, Karmpaliotis D, Parikh SA, Weisz G, Collins MB, Privitera LT, Rabbani LE, Leon MB, Moses JW, Stone GW, Kirtane AJ, Mintz GS, Maehara A. Impact of Nonobstructive Left Main Coronary Artery Atherosclerosis on Long-Term Mortality. JACC Cardiovasc Interv. 2022;15:2206-2217.
  18. 18. Usui E, Matsumura M, Smilowitz NR, Mintz GS, Saw J, Kwong RY, Hada M, Mahmud E, Giesler C, Shah B, Bangalore S, Razzouk L, Hoshino M, Marzo K, Ali ZA, Bairey Merz CN, Sugiyama T, Har B, Kakuta T, Hochman JS, Reynolds 6 HR, Maehara A. Coronary morphological features in women with non-ST-segment elevation MINOCA and MI-CAD as assessed by optical coherence tomography. Eur Heart J Open. 2022; doi: 10.1093/ehjopen/oeac058.
  19. 19. Wang L, Maehara A, Zhang X, Lv R, Qu Y, Guo X, Zhu J, Wu Z, Billiar KL, Zheng J, Chen L, Ma G, Mintz GS, Tang D. Quantification of patient-specific coronary material properties and their correlations with plaque morphological characteristics: An in vivo IVUS study. Int J Cardiol. 2023;371:21-27.
  20. 20. Wang L, Maehara A, Lv R, Guo X, Zheng J, Billiar KL, Mintz GS, Tang D. Image-Based Finite Element Modeling Approach for Characterizing In Vivo Mechanical Properties of Human Arteries. J Funct Biomater. 2022;13:147.
  21. 21. Chen Z, Matsumura M, Mintz GS, Noguchi M, Fujimura T, Usui E, Seike F, Hu X, Jin G, Li C, Salem H, Fall KN, Shlofmitz E, Kirtane AJ, Cao JJ, Moses JW, Ali ZA, Jeremias A, Shlofmitz RA, Maehara A. Prevalence and Impact of Neoatherosclerosis on Clinical Outcomes After Percutaneous Treatment of Second-Generation Drug-Eluting Stent Restenosis. Circ Cardiovasc Interv. 2022; doi: 10.1161/CIRCINTERVENTIONS.121.011693.
  22. 22. Lundy EF, Karimi Galougahi K, Dominguez-Sulca D, Chowdhury E, Thomas SV, Porter CR, Mintz GS, Matsumura M, Maehara A, Cohen DJ, Moses JW, Shlofmitz ES, Jeremias A, West NEJ, Robinson NB, Shlofmitz RA, Ali ZA. Visualizing Inside Conduits-Intraoperative Screening of Grafts by Optical Coherence Tomography. Ann Thorac Surg. 2023;115:266- 271.