Clinical Trials

  • Principal Investigator:

    Susheel Kumar Kodali, MD
    This is designed for patients with severe, symptomatic mitral regurgitation who are not candidates for conventional mitral repair.
  • Principal Investigator:

    Muredach Patrick Reilly, MD
    As an academic medical center, we are always working to improve patient and population health. One way that research is supported here is through the Columbia University Biobank (CUB). A biobank is a collection of biological samples and health data that is collected during a patient's medical care. The goal of a biobank is to provide materials for researchers to use in their scientific studies of health conditions such as cancer, heart disease, and diabetes. People who participate in a biobank help researchers find treatments and cures, and they also help their community benefit from improved...
  • Principal Investigator:

    Sahil A. Parikh, MD
    This study is to collect information about the symptoms and treatments of patient who have severely clogged arteries and treated with commercially available Boston Scientific Corporation drug-eluting devices marketed for treatment of lesions located in the peripheral vasculature. If you choose to be part of this research, we will ask you to be involved in office visits at 6, 12, and 24 months as well as follow-up at 36, 48 and 24 months will be completed in office or remotely. Your involvement in the research will last for 5 years. There are no or minimal risks from participating in this...
  • Principal Investigator:

    Sahil A. Parikh, MD
    This is a prospective, multicentre observational study to evaluate the BioMimics 3D Vascular Stent System in the treatment of peripheral arterial disease. The purpose of the study is to collect detailed information on the BioMimics 3D stent performance when used according to standard medical care. A minimum of 500 patients will be enrolled in a two-year recruitment period at up to 40 sites. Patients will be evaluated at 30 days then 12, 24, and 36 months.
  • Principal Investigator:

    Susheel Kumar Kodali, MD
    This is a randomized controlled trial (RCT) that will compare the clinical outcome of MitraClip device versus surgical repair in patients with severe primary MR who are at moderate surgical risk and whose mitral valve has been determined to be suitable for correction by MV repair surgery by the cardiac surgeon on the local site heart team. In this trial, each subject will be followed until their 10-year visit. Clinical Investigation visits will occur at Screening (for determination of eligibility), Baseline (after confirmation of eligibility), Index Procedure, Discharge, 30 days, 6 months, 1...
  • Principal Investigator:

    Susheel Kumar Kodali, MD
    Aortic stenosis (AS) or narrowing of the arteries remains one of the most common valvular diseases in the Western population requiring intervention. The deterioration of the aortic valve is more common in the older population and usually along with coronary artery disease (CAD) requires the need for treatment. This is a study that is collecting safety and effectiveness data in a high or extreme surgical risk patient population with symptomatic, severe native AS and who meet eligibility criteria for implantation of the PorticoNG valve. The Portico NG Valve (along with the delivery and loading...
  • Principal Investigator:

    Marwah Abdalla, MD
    The Center for Behavioral Cardiovascular Health (CBCH) is conducting a research study to examine the impact that sleep hours have on blood pressure (BP) levels during sleep. Two-part screening to determine eligibility for this study involves a) answering questionnaires and b) documenting daily average sleep duration (how long you sleep) over the course of a 2-week period. Participation in the research study involves 1-4 study visits, wearing a Fitbit activity monitoring device for an additional 8 weeks, wearing a blood pressure measurement device and a heart monitoring patch device for 2...
  • Principal Investigator:

    Gabriel Tal Sayer, MD
    The purpose of this trial is to evaluate the feasibility of the Doraya Catheter and measure clinical performance and safety endpoints.
  • Principal Investigator:

    Jeffrey W Moses, MD
    The purpose of this study is to demonstrate that the Impella Hemodynamic Platform (the StudyDevice) is safe and that measurements obtained are as good as currently used methods. This includes how much pressure the heart is generating and how much blood your heart is pumping during the PCI. PCI is a surgical procedure that uses a catheter (a thin flexible tube) to place a small structure called a stent to open up blood vessels in the heart that have been narrowed by plaque buildup. The TheImpella device will be placed via the a femoral artery and delivers up to 3.5 liters of blood per minute...
  • Principal Investigator:

    Daichi Shimbo, MD
    We are conducting a research study in adults to test whether blood pressure (BP) measured in a clinic setting without a technician present is comparable to blood pressure levels while awake outside of the clinic on an Ambulatory Blood Pressure Monitoring (ABPM) device. We will also test whether asleep blood pressure can be accurately determined using a home blood pressure monitoring device, called HBPM. Eligible participants include English or Spanish-speaking adults who don't have cardiovascular disease and are NOT currently taking a blood pressure-lowering medication. Study participation...

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