Clinical Trials
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Principal Investigator:
Robert J. Sommer, MDThis is a prospective, multicenter, open-label, single-arm study that seeks to confirm and describe the safety and effectiveness of the GSO device as observed in the REDUCE pivotal IDE study. It is also designed to demonstrate acceptable performance of the GSO device in patients treated with percutaneous, transcatheter PFO closure plus anti-platelet medical management compared to performance goals derived from REDUCE study results. -
Principal Investigator:
Kelly Marie Axsom, MDThe ALLEVIATE-HF study is a prospective, randomized, multi-site, interventional, investigational device exemption (IDE) study. The purpose of the study is to gain experience with utilization of an integrated device diagnostic-based risk stratification algorithm to guide patient care in subjects with NYHA class II and III heart failure. The study will utilize the market-released Reveal LINQ Insertable Cardiac Monitor with an investigational ALLEVIATE-HF RAMware download. The study will enroll up to 300 subjects at up to 30 sites in the US and will characterize the safety of the patient... -
Principal Investigator:
Susheel Kumar Kodali, MDThis is designed for patients with severe, symptomatic mitral regurgitation who are not candidates for conventional mitral repair. -
Principal Investigator:
Muredach Patrick Reilly, MDAs an academic medical center, we are always working to improve patient and population health. One way that research is supported here is through the Columbia University Biobank (CUB). A biobank is a collection of biological samples and health data that is collected during a patient's medical care. The goal of a biobank is to provide materials for researchers to use in their scientific studies of health conditions such as cancer, heart disease, and diabetes. People who participate in a biobank help researchers find treatments and cures, and they also help their community benefit from improved... -
Principal Investigator:
Sahil A. Parikh, MDThis study is to collect information about the symptoms and treatments of patient who have severely clogged arteries and treated with commercially available Boston Scientific Corporation drug-eluting devices marketed for treatment of lesions located in the peripheral vasculature. If you choose to be part of this research, we will ask you to be involved in office visits at 6, 12, and 24 months as well as follow-up at 36, 48, and 24 months will be completed in office or remotely. Your involvement in the research will last for 5 years. There are no or minimal risks from participating in this... -
Principal Investigator:
Susheel Kumar Kodali, MDThe early feasibility study (EFS) of the Cardioband Tricuspid System is a prospective, single-arm, multi-center study to evaluate the safety and performance of the Cardioband Tricuspid System. The Edwards Cardioband Tricuspid Valve Reconstruction System is intended for patients with tricuspid regurgitation deemed to be potential candidates for transcatheter tricuspid valve reconstruction with the Edwards Cardioband Tricuspid Valve Reconstruction System by the local Heart Team. -
Principal Investigator:
Susheel Kumar Kodali, MDThe study is designed to compare the safety and effectiveness of the PASCAL System to the MitraClip System for reduction of degenerative mitral regurgitation. -
Principal Investigator:
Robert J. Sommer, MDThis study will evaluate Patent Foramen Ovale (PFO) closure for migraine headache relief using a device called the GORE CARDIOFORM Septal Occluder. A patent foramen ovale (PFO) is a hole in the heart that didn't close the way it should after birth. During fetal development, a small flap-like opening the foramen ovale is normally present in the wall between the right and left upper chambers of the heart (atria). Most patients with a PFO do not have any symptoms. However, the condition may play a role in migraine headaches and it increases the risk of stroke, transient ischemic attack (stroke... -
Principal Investigator:
Daichi Shimbo, MDThe measurement of blood pressure used to determine if a person has high blood pressure (also known as hypertension) and whether their blood pressure is controlled while taking medications that lower blood pressure. For many people, blood pressure levels are different when measured in a providers office versus during normal daily activities outside of the office. There are two ways to measure blood pressure outside of the office: ambulatory blood pressure monitoring (ABPM) and home blood pressure monitoring (HBPM). The best approach to measure blood pressure outside of the office is unclear... -
Principal Investigator:
Daichi Shimbo, MDThe measurement of blood pressure used to determine if a person has high blood pressure (also known as hypertension) and whether their blood pressure is controlled while taking medications that lower blood pressure. For many people, blood pressure levels are different when measured in a providers office versus during normal daily activities outside of the office. There are two ways to measure blood pressure outside of the office: ambulatory blood pressure monitoring (ABPM) and home blood pressure monitoring (HBPM). The best approach to measure blood pressure outside of the office is unclear...