Clinical Trials

  • Principal Investigator:

    Andrew Jeffrey Einstein, MD
    We are seeking healthy volunteers and people who have tested positive for COVID-19 in the past. Our study is looking at how coronavirus affects the heart after recovery. If you enroll, you will be given an echocardiogram and a cardiac magnetic resonance imaging (MRI) scan, and you will be asked to provide a blood sample. An echocardiogram is a test that uses sound waves to get a picture of your heart. A cardiac MRI scan uses radio waves to get another kind of picture of your heart. For the MRI, you will receive an injection of a contrast agent, which is safe for qualified participants. There...
  • Principal Investigator:

    Andrew Jeffrey Einstein, MD
    We are seeking healthy volunteers and people who have tested positive for COVID-19 in the past. Our study is looking at how coronavirus affects the heart after recovery. If you enroll, you will be given an echocardiogram and a cardiac magnetic resonance imaging (MRI) scan, and you will be asked to provide a blood sample. An echocardiogram is a test that uses sound waves to get a picture of your heart. A cardiac MRI scan uses radio waves to get another kind of picture of your heart. For the MRI, you will receive an injection of a contrast agent, which is safe for qualified participants. There...
  • Principal Investigator:

    Mathew Maurer, MD
    A drug study looking at the effects of 10 mg Dapagliflozin vs. Placebo in patients with Heart Failure and Preserved Ejection Fraction (HFpEF) with either diabetes or pre-diabetes. Subjects are being asked to take part in this study because they have heart failure (inability of the heart to pump blood with normal efficiency). The purpose of this study is to find out if a drug called dapagliflozin would be effective in improving the blood tests and symptoms related to their heart failure. To do this, dapagliflozin will be compared with placebo. The placebo will look like dapagliflozin but will...
  • Principal Investigator:

    Susheel Kumar Kodali, MD
    The study is designed to to compare the safety and effectiveness of the PASCAL System to the MitraClip System for reduction of degenerative mitral regurgitation.
  • Principal Investigator:

    Susheel Kumar Kodali, MD
    The study is to determine whether aortic valve replacement is helpful for patients who have severe, calcific, aortic stenosis (a narrowing of the aortic heart valve, where calcium has attached to the valve surface, resulting in obstructed blood flow) and do not have symptoms.
  • Principal Investigator:

    Andrew Jeffrey Einstein, MD
    Phase 3 open-label, multicenter Study of Flurpiridaz Injection for PET Imaging for assessment of Myocardial perfusion in patients referred for Invasive Coronary Angiography because of suspected Coronary Artery Disease
  • Principal Investigator:

    Ajay J. Kirtane, MD
    The purpose of this study is to collect data for evaluating VFR (Virtual Flow Reserve) in comparison with standard FFR (Fractional Flow Reserve) when patients undergo a percutaneous coronary intervention (PCI) to treat blockage or narrowing in the heart artery or arteries.
  • Principal Investigator:

    Hirad Yarmohammadi, MD
    We are doing this study to gather information on participants returning at time of Cardiovascular Implantable Electronic Device (CIED) change-out or revision who underwent a device implantation with either a CanGaroo envelope, Tyrx envelope, or no envelope. A CIED is a device implantable inside the body, able to conduct pacing of the heart and therefore capable of correcting most life-threatening abnormal heart rhythms. People who have had surgery to implant a medical device that helps their heart, may have had their surgery done in slightly different ways. In this study, the investigators...
  • Principal Investigator:

    Frederick Arthur Ehlert, MD
    The purpose of this registry is to collect information over time about how Medtronic products are working and/or the outcome of the treatment. The registry will be used to support post-market surveillance/monitoring activities and post-approval studies (e.g., to collect safety and performanceinformation). In addition, it will be used to obtain clinical evidence for the development and improvement of medical devices, therapies, device guidelines and patient services/solutions. The Registry data is intended to benefit and support interests of patients, hospitals, clinicians, regulatory bodies,...
  • Principal Investigator:

    Susheel Kumar Kodali, MD
    The Millipede Feasibility Study is a prospective, open-label, single-arm study to assess the safety and feasibility of the Millipede Transcatheter Annuloplasty Ring System in subjects with functional mitral regurgitation. The Millipede Annuloplasty Ring System is a novel transcatheter, fully adjustable, complete annuloplasty repair device for the treatment of mitral regurgitation. The device is designed to mimic a widely used surgical intervention with a percutaneous therapy. As such, it potentially offers a less invasive and safer treatment for mitral regurgitation in comparison to surgery...

Pages