Clinical Trials

  • We are doing this research study to learn more about human blood cells called monocytes. Currently, there are several well-documented types of monocytes, each having unique roles in our immune system and in heart and vascular diseases. This study will examine the genetic make-up of monocytes to identify new and unique subsets across different cardiovascular (CV) risk states, including Type II Diabetes (DM2), tobacco smoking, and high cholesterol. We are seeking to understand if some types of monocytes are more prevalent within specific cardiovascular risk states than others.
  • We are doing this research study to learn more about human blood cells called monocytes. Currently, there are several well-documented types of monocytes, each having unique roles in our immune system and in heart and vascular diseases. This study will examine the genetic make-up of monocytes to identify new and unique subsets across different cardiovascular (CV) risk states, including Type II Diabetes (DM2), tobacco smoking, and high cholesterol. We are seeking to understand if some types of monocytes are more prevalent within specific cardiovascular risk states than others.
  • We are doing this research study to learn more about human blood cells called monocytes. Currently, there are several well-documented types of monocytes, each having unique roles in our immune system and in heart and vascular diseases. This study will examine the genetic make-up of monocytes to identify new and unique subsets across different cardiovascular (CV) risk states, including Type II Diabetes (DM2), tobacco smoking, and high cholesterol. We are seeking to understand if some types of monocytes are more prevalent within specific cardiovascular risk states than others.
  • We are doing this research study to learn more about human blood cells called monocytes. Currently,there are several well-documented types of monocytes, each having unique roles in our immune system and in heart and vascular diseases. This study will examine the genetic make-up of monocytes to identify new and unique subsets across different cardiovascular (CV) risk states, including Type II Diabetes (DM2), tobacco smoking, and high cholesterol. We are seeking to understand if some types of monocytes are more prevalent within specific cardiovascular risk states than others.
  • The phrase sitting is the new smoking has been coined due to an increase of excessive sitting in middle- and older-aged adults. However, there are currently no specific guidelines for the best way to break up long periods of sitting. This study will look at the effect of breaking up sitting periods with movement breaks on blood sugar levels. We are looking for non-smoking, otherwise healthy adults,who sit for most of their day with little to no exercise. Participants will be asked to sit taking 1 or 5-minute walking breaks every 30 or 60 minutes over an 8-hour period.
  • The Center for Behavioral Cardiovascular Health (CBCH) is conducting a research study to examine the relationship between sleep and nighttime blood pressure levels and whether this relationship has something to do with the way our nervous system functions. Qualified participants who complete a 2 day study that includes an overnight sleep assessment at the Columbia University Cardiopulmonary Sleep and Ventilation Disorders Center are eligible for a $200 compensation.
  • This is a research study to evaluate the use of a device to treat patients with Heart Failure (HF) who have moderate aortic stenosis (AS). The Edwards SAPIEN 3 has already been approved by the FDA for use in patients who require an aortic valve replacement due to severe aortic stenosis. This is an international, multicenter, randomized, open-label, clinical trial comparing the safety and effectiveness of TAVR(Transcatheter Aortic Valve Replacement) with the Edwards SAPIEN 3 THV (transcatheter heart valve) and medical therapy to medical therapy alone in HF patients with moderate AS.

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