Clinical Trials
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Principal Investigator:
Torsten Peter Vahl, MDThe objective of the study is to evaluate the safety and efficacy of the JenaValve Pericardial TAVR system when treating patients with aortic regurgitation. Aortic Regurgitation is a condition that develops when the heart's aortic valve does close tightly, therefore the blood leaks back into the heart chamber. The JenaValve Pericardial TAVR system will be used to treat this condition and restore proper flow blood. Treatment of aortic regurgitation with the JenaValve provides a controlled valve release and deployment during the entire implantation procedure under beating heart conditions,... -
Principal Investigator:
Susheel Kumar Kodali, MDThis is designed for patients with severe, symptomatic mitral regurgitation who are not candidates for conventional mitral repair. -
Principal Investigator:
Susheel Kumar Kodali, MDThe goal of this early feasibility study is to gain initial insight into the basic safety and performance of transluminal (through the blood vessels) implantation of the PASCAL System's implant (composed of man-made materials). We are trying to evaluate the safety and performance of the PASCAL System with Optimal Medical Therapy (OMT) (also known as standard of care) compared to OMT alone in participants with symptomatic severe tricuspid regurgitation who may not be ideal candidates for tricuspid valve surgery (tricuspid valve repair that is performed via open-heart surgery) and may be... -
Principal Investigator:
Muredach Patrick Reilly, MDAs an academic medical center, we are always working to improve patient and population health. One way that research is supported here is through the Columbia University Biobank (CUB). A biobank is a collection of biological samples and health data gathered during a patient's medical care. Participants in a biobank help researchers find treatments and cures, benefiting their community through improved health. It takes everyone working together to make important medical discoveries! Participation is completely voluntary and involves just a few steps: 1. Be a patient of CUIMC/NYP. 2. Review and... -
Principal Investigator:
Vivian Gar-Yan Ng, MDThe purpose of this study is to find out, in patients with CAD who had successful TAVR with a balloon expandable heart valve, whether restoring blood flow to all blocked or narrowed arteries via PCI using coronary stents (metal scaffold) is better than treating the coronary artery disease with medications only following TAVR. The study will also compare measurements of hemodynamics (blood flow and blood pressure) that are taken during on-table procedures (TAVR and PCI) with those taken by echocardiography (heart ultrasound). These measurements are all taken as a part of standard practice for... -
Principal Investigator:
Andrew J. Einstein, MD, PhDWe are seeking patients that have had a pre-COVID heart CT scan (Coronary Computed Tomography Angiography) that was performed at Columbia University Irving Medical Center/NewYork-Presbyterian Hospital before March of 2020. For this study, half of patients will be required to have had COVID-19 symptoms (e.g., fever, cough, shortness of breath) and would have tested positive for COVID-19 (by an FDA-approved test). The other half will not have had a prior diagnosis of COVID-19. If you enroll in the study, you will be given a CT, asked to provide a blood sample as well as answer the study... -
Principal Investigator:
Andrew J. Einstein, MD, PhDWe are seeking patients that have had a pre-COVID heart CT scan (Coronary Computed Tomography Angiography) that was performed at Columbia University Irving Medical Center/NewYork-Presbyterian Hospital before March of 2020. For this study, half of patients will be required to have had COVID-19 symptoms (e.g., fever, cough, shortness of breath) and would have tested positive for COVID-19 (by an FDA-approved test). The other half will not have had a prior diagnosis of COVID-19. If you enroll in the study, you will be given a CT, asked to provide a blood sample as well as answer the study... -
Principal Investigator:
Sahil A. Parikh, MDThis study aims to collect information about the symptoms and treatments of patients who have severely clogged arteries and are treated with commercially available Boston Scientific Corporation drug-eluting devices marketed for the treatment of lesions located in the peripheral vasculature. Participation in the study is expected to last for up to two (2) years. If you choose to be part of this research, we will ask you to be involved in routine follow-up visits at 6 months, 1 year, and every year thereafter for up to 2 years. Additionally, you may be asked to complete a survey before being... -
Principal Investigator:
Susheel Kumar Kodali, MDThe study is designed to compare the safety and effectiveness of the PASCAL System to the MitraClip System for reduction of degenerative mitral regurgitation. -
Principal Investigator:
Ari Shechter, PhDThe purpose of this study to examine the long-term general psychological symptoms, and identify the predictors of these psychological symptoms. The sustained psychological toll of working in a high-stress environment can have downstream impacts on health. It is therefore important to also consider how psychological factors influence physical health, for example, cardiovascular risk in ED staff. As part of the study, we will also determine the prevalence and predictors of long-term psychological symptoms in ED clinicians who worked during the COVID-19 pandemic and characterize the relationship...