Barry Michael Fine, MD, PHD
Overview
Barry Fine MD PhD is a physician scientist whose clinical and research interests center on cardiogenetics and molecular cardiology. His research utilizes stem cells and engineered human heart tissue to model cardiac disease for drug and gene therapy discovery. His lab is one of the main sites of the NIH funded tissue engineering resource center (www.nextgenterc.com) whose mission is to improve disease modeling across all organs by advancing tissue engineering. Using these cutting-edge methods, Dr. Fine has active research areas involving heart attacks (myocardial infarction), inherited disease of the heart muscle (cardiomyopathies) and novel druggable signaling pathways in heart cells to improve heart function. Additionally, Dr. Fine is also involved in experimental gene therapy trials for patients with inherited cardiomyopathies and arrhythmias through his cardiogenetics clinic. He is currently the Esther and Oded Aboodi Scholar and an Assistant Professor of Medicine in the Division of Cardiology as well as the assistant program director of the cardiology fellowship.
Academic Appointments
- Assistant Professor of Medicine
Hospital Affiliations
- NewYork-Presbyterian / Columbia University Irving Medical Center
Gender
- Male
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Credentials & Experience
Education & Training
- MD, PhD, Columbia University College of Physicians and Surgeons
- Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
- Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center
Board Certifications
- Cardiovascular Disease
- Internal Medicine
Honors & Awards
- 2023 - Esther and Oded Aboodi Scholar, Columbia University
- 2017- Louis J. Gerstner Scholar, Columbia University
- 2013 - Medicine Teaching Award, New York Hospital
- 2011 - Clinician Resident of the Year, New York Hospital
- 2009 - Alpha Omega Alpha Honor Society, Columbia University
- 2009 - Maxwell Award for Excellence in Pulm/Critical Care Medicine
- 2009 - Titus Munson Coan Prize for Outstanding Biological Project
Research
Grants
07/23-06/28 NIH R01 HL166387 $1,769,700 (PI- Fine)
STK25 phosphorylates PRKAR1A to regulate PKA signaling
Role: Principal Investigator
08/19-7/24 NIH P41 EB 027062 $1,374,245. (MPI: Vunjak-Novakovic)
Tissue Engineering Resource Center
Role: TR&D3 Principal Investigator
1/20-12/24 Abramov Family Foundation $242,739 (PI- Fine)
Drug discovery initiative in restrictive cardiomyopathy
Role: Principal Investigator
12/23-11/25 New York Community Trust $350,000 (PI-Fine)
Improving Cellular Resiliency During a Heart Attack
Role: Principal Investigator
07/23-06/24 Columbia University Technology Ventures $75,000 (PI-Fine)
Covyv: Keeping Heart Cells Alive
Role: Principal Investigator
08/23-07/24 Irving Precision Medicine Pilot Award $100,000 (PI: Shin)
Impaired cellular energetics and lipid metabolism in human iPS-cardiomyocytes
Role: Co-Investigator
Selected Publications
For a complete list of publications, please visit PubMed.gov