Ersilia M. DeFilippis, MD

Advanced Heart Failure and Transplant Cardiology
Internal Medicine
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Dr. Ersilia M. DeFilippis, FACC is an Assistant Professor of Cardiology and Advanced Heart Failure and Transplant Cardiologist at Columbia University Irving Medical Center. 

She graduated from Yale University summa cum laude with a Bachelors of Arts in Women’s Studies and a concentration in Women’s Health. After graduating from Weill Cornell Medical College with an MD with Honors in Research, she completed her Internal Medicine residency at Brigham and Women’s Hospital in Boston. Subsequently, she finished her fellowships in cardiovascular disease and advanced heart failure and transplant cardiology at Columbia University Irving Medical Center. She is board certified in internal medicine, cardiology, and advanced heart failure and transplant cardiology. Her clinical interests include peripartum cardiomyopathy, pregnancy and cardiovascular disease, heart failure, heart transplantation, and mechanical circulatory support. 

Her research interests include sex-specific outcomes and disparities in advanced heart failure and transplantation as well as the intersection of heart failure and cardio-obstetrics. She is also interested in health disparities and health equity more broadly.

She has over 170 peer-reviewed publications and has published in leading journals including JAMA Cardiology, Journal of Heart and Lung Transplantation, Circulation: Heart Failure; JACC and JACC: Heart Failure. She has also given invited talks at multiple national and international conferences.  She was a Co-Chair of the ISHLT Consensus Statement on Reproductive Health after Thoracic Transplantation. She is also a member of the Executive Committee of the Women’s Health Community of Practice of the American Society of Transplantation and the Diverse Populations Editor for the Journal of Cardiac Failure. She is on the Founding Board of Directors for the Equity in Heart Transplant Project. 

Areas of Expertise / Conditions Treated

  • Heart Failure
  • Pulmonary Hypertension

Academic Appointments

  • Assistant Professor of Medicine

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center


  • Female

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Credentials & Experience

Education & Training

  • Cornell University Medical College
  • Internship: Brigham and Women's Hospital
  • Residency: Brigham and Women's Hospital
  • Fellowship: NewYork-Presbyterian/Columbia University Medical Center


Selected Publications

1: Joyce E, McIivennan CK, Esquivel JH, Sauer AJ, Correa A, Blumer V, Youmans
QR, Alvarez-Garcia J, Chang H, Overbey J, Deych E, Sinha SS, Morris A,
Defilippis EM, Reza N, Code J, Hajduczok AG, Fudim M, Rollins B, Vader JM, Pina
IL, Teuteberg J, Zieroth S, Starling RC, Gulati M, Mentz RJ, Lala A.
Participating in the Peer Review Process: The Journal of Cardiac Failure
Construct. J Card Fail. 2022 Dec 16:S1071-9164(22)01209-X. doi:
10.1016/j.cardfail.2022.11.007. Epub ahead of print. PMID: 36529605.

2: Kittleson MM, DeFilippis EM, Bhagra CJ, Casale JP, Cauldwell M, Coscia LA,
D'Souza R, Gaffney N, Gerovasili V, Ging P, Horsley K, Macera F, Mastrobattista
JM, Paraskeva MA, Punnoose LR, Rasmusson KD, Reynaud Q, Ross HJ, Thakrar MV,
Walsh MN. Reproductive health after thoracic transplantation: An ISHLT expert
consensus statement. J Heart Lung Transplant. 2022 Oct 26:S1053-2498(22)02177-5.
doi: 10.1016/j.healun.2022.10.009. Epub ahead of print. PMID: 36528467.

3: Rubinstein G, Lotan D, Moeller CM, DeFilippis EM, Slomovich S, Oren D,
Yuzefpolskaya M, Sayer G, Uriel N. Sex differences in patients undergoing heart
transplantation and LVAD therapy. Expert Rev Cardiovasc Ther. 2022
Nov;20(11):881-894. doi: 10.1080/14779072.2022.2149493. PMID: 36409479.

4: Clerkin KJ, Topkara VK, Farr MA, Jain R, Colombo PC, Restaino S, Sayer G,
Castillo M, Lam EY, Chernovolenko M, Yuzefpolskaya M, DeFilippis E, Latif F,
Zorn E, Takeda K, Johnson LL, Uriel N, Einstein AJ. Noninvasive Physiologic
Assessment of Cardiac Allograft Vasculopathy Is Prognostic for Post-Transplant
Events. J Am Coll Cardiol. 2022 Oct 25;80(17):1617-1628. doi:
10.1016/j.jacc.2022.08.751. PMID: 36265957; PMCID: PMC9758655.

5: Siddiqi HK, Defilippis EM, Biery DW, Singh A, Wu WY, Divakaran S, Berman AN,
Rizk T, Januzzi JL, Bohula E, Stewart G, Carli MD, Bhatt DL, Blankstein R.
Mortality and Heart Failure Hospitalization Among Young Adults With and Without
Cardiogenic Shock After Acute Myocardial Infarction. J Card Fail. 2022 Sep
18:S1071-9164(22)00710-2. doi: 10.1016/j.cardfail.2022.08.012. Epub ahead of
print. PMID: 36130688.

6: Loiseau P, Foret T, DeFilippis EM, Risse J, Etienne AD, Dufrost V, Moulinet
T, Erkan D, Devilliers H, Wahl D, Zuily S. Risk of livedo with antiphospholipid
antibodies in patients with systemic lupus erythematosus: A systematic review
and meta-analysis. Lupus. 2022 Nov;31(13):1595-1605. doi:
10.1177/09612033221126852. Epub 2022 Sep 15. PMID: 36112747.

7: Golob S, Batra J, DeFilippis EM, Uriel M, Carey M, Gaine M, Mabasa A, Fried
J, Raikelkar J, Restaino S, Hi Lee S, Latif F, Yuzefpolskaya M, Colombo PC, Choe
J, Majure D, Jennings D, Pereira MR, Clerkin K, Sayer G, Uriel N. Letermovir for
cytomegalovirus prophylaxis in high-risk heart transplant recipients. Clin
Transplant. 2022 Sep 10:e14808. doi: 10.1111/ctr.14808. Epub ahead of print.
PMID: 36086937.

8: DeFilippis EM, Loccoh EC, Simpson D, Ibrahim NE. The Gatekeepers to
Transplantation: Who Are We Keeping Out? Am J Cardiol. 2022 Oct 1;180:170-172.
doi: 10.1016/j.amjcard.2022.07.005. Epub 2022 Aug 6. PMID: 35945041.

9: Butt JH, Dewan P, DeFilippis EM, Biering-Sørensen T, Docherty KF, Jhund PS,
Kosiborod MN, Martinez FA, Bengtsson O, Johansen ND, Langkilde AM, Sjöstrand M,
Vaduganathan M, Solomon SD, Sabatine MS, Køber L, Fiuzat M, McMurray JJV.
Effects of Dapagliflozin According to the Heart Failure Collaboratory Medical
Therapy Score: Insights From DAPA-HF. JACC Heart Fail. 2022 Aug;10(8):543-555.
doi: 10.1016/j.jchf.2022.03.009. Epub 2022 Jun 8. PMID: 35902157.

10: Foote MB, Jain N, Rome BN, DeFilippis EM, Powe CE, Yialamas MA. Association
of Perceived Role Misidentification With Use of Role Identity Badges Among
Resident Physicians. JAMA Netw Open. 2022 Jul 1;5(7):e2224236. doi:
10.1001/jamanetworkopen.2022.24236. PMID: 35900759; PMCID: PMC9335144.

11: Ebong IA, DeFilippis EM, Hamad EA, Hsich EM, Randhawa VK, Billia F, Kassi M,
Bhardwaj A, Byku M, Munagala MR, Rao RA, Hackmann AE, Gidea CG, DeMarco T, Hall
SA. Special Considerations in the Care of Women With Advanced Heart Failure.
Front Cardiovasc Med. 2022 Jul 11;9:890108. doi: 10.3389/fcvm.2022.890108. PMID:
35898277; PMCID: PMC9309391.

12: Clark KAA, Defilippis EM, Morris AA. Breaking the Bank: The Financial Burden
of Living With Heart Failure. J Card Fail. 2022 Sep;28(9):1434-1436. doi:
10.1016/j.cardfail.2022.07.004. Epub 2022 Jul 20. PMID: 35870751.

13: Hedvat J, Lange NW, Salerno DM, DeFilippis EM, Kovac D, Corbo H, Chen JK,
Choe JY, Lee JH, Anamisis A, Jennings DL, Codispodo G, Shertel T, Brown RS Jr,
Pereira MR. COVID-19 therapeutics and outcomes among solid organ transplant
recipients during the Omicron BA.1 era. Am J Transplant. 2022
Nov;22(11):2682-2688. doi: 10.1111/ajt.17140. Epub 2022 Jul 18. PMID: 35801839;
PMCID: PMC9349644.

14: Defilippis EM, Allen LA, Bhatt AS, Joseph S, Kittleson M, Vardeny O, Drazner
MH, Lala A. Vaccines, Antibodies and Donors: Varying Attitudes and Policies
Surrounding COVID-19 and Heart Transplantation. J Card Fail. 2022
Dec;28(12):1727-1732. doi: 10.1016/j.cardfail.2022.05.009. Epub 2022 Jun 16.
PMID: 35718306; PMCID: PMC9212876.

15: DeFilippis EM, Topkara VK, Kirtane AJ, Takeda K, Naka Y, Garan AR.
Mechanical Circulatory Support for Right Ventricular Failure. Card Fail Rev.
2022 Apr 21;8:e14. doi: 10.15420/cfr.2021.11. PMID: 35516793; PMCID: PMC9062706.

16: Defilippis EM, Truby LK, Clerkin KJ, Donald E, Sinnenberg L, Varshney AS,
Cogswell R, Kittleson MM, Haythe JH, Givertz MM, Hsich EM, Agarwal R, Topkara
VK, Farr M. Increased Opportunities for Transplantation for Women in the New
Heart Allocation System. J Card Fail. 2022 Jul;28(7):1149-1157. doi:
10.1016/j.cardfail.2022.03.354. Epub 2022 Apr 22. PMID: 35470056.

17: DeFilippis EM. Infertility: A Fertile Ground for Heart Failure? J Am Coll
Cardiol. 2022 Apr 26;79(16):1604-1605. doi: 10.1016/j.jacc.2022.02.019. PMID:

18: Imran TF, Mohebali D, Lopez D, Goli RR, DeFilippis EM, Truong S, Bello NA,
Gaziano JM, Djousse L, Coglianese EE, Feinberg L, Wu WC, Choudhary G, Arany Z,
Kociol R, Sabe MA. NT-proBNP and predictors of event free survival and left
ventricular systolic function recovery in peripartum cardiomyopathy. Int J
Cardiol. 2022 Jun 15;357:48-54. doi: 10.1016/j.ijcard.2022.03.052. Epub 2022 Mar
28. PMID: 35358637.

19: DeFilippis EM, Blumer V, Mentz RJ, Agarwal R, Haythe JH, Kittleson M. In-
Hospital Outcomes in Pregnancy After Heart Transplantation. Am J Cardiol. 2022
Jun 1;172:68-72. doi: 10.1016/j.amjcard.2022.02.026. Epub 2022 Mar 21. PMID:

20: DeFilippis EM, Echols M, Adamson PB, Batchelor WB, Cooper LB, Cooper LS,
Desvigne-Nickens P, George RT, Ibrahim NE, Jessup M, Kitzman DW, Leifer ES,
Mendoza M, Piña IL, Psotka M, Senatore FF, Stein KM, Teerlink JR, Yancy CW,
Lindenfeld J, Fiuzat M, O'Connor CM, Vardeny O, Vaduganathan M. Improving
Enrollment of Underrepresented Racial and Ethnic Populations in Heart Failure
Trials: A Call to Action From the Heart Failure Collaboratory. JAMA Cardiol.
2022 May 1;7(5):540-548. doi: 10.1001/jamacardio.2022.0161. PMID: 35319725;
PMCID: PMC9098689.

21: DeFilippis EM, Clerkin KJ, Givens RC, Kleet A, Rosenblum H, O'Connell DC,
Topkara VK, Bijou R, Sayer G, Uriel N, Takeda K, Farr MA. Impact of
socioeconomic deprivation on evaluation for heart transplantation at an urban
academic medical center. Clin Transplant. 2022 Jun;36(6):e14652. doi:
10.1111/ctr.14652. Epub 2022 May 3. PMID: 35315535.

22: DeFilippis EM, Khush KK, Farr MA, Fiedler A, Kilic A, Givertz MM. Evolving
Characteristics of Heart Transplantation Donors and Recipients: JACC Focus
Seminar. J Am Coll Cardiol. 2022 Mar 22;79(11):1108-1123. doi:
10.1016/j.jacc.2021.11.064. PMID: 35300823.

23: Varshney AS, DeFilippis EM, Cowger JA, Netuka I, Pinney SP, Givertz MM.
Trends and Outcomes of Left Ventricular Assist Device Therapy: JACC Focus
Seminar. J Am Coll Cardiol. 2022 Mar 22;79(11):1092-1107. doi:
10.1016/j.jacc.2022.01.017. PMID: 35300822.

24: DeFilippis EM, Beale A, Martyn T, Agarwal A, Elkayam U, Lam CSP, Hsich E.
Heart Failure Subtypes and Cardiomyopathies in Women. Circ Res. 2022 Feb
18;130(4):436-454. doi: 10.1161/CIRCRESAHA.121.319900. Epub 2022 Feb 17. Erratum
in: Circ Res. 2022 Mar 18;130(6):e21. Erratum in: Circ Res. 2022 Apr
29;130(9):e25. PMID: 35175847.

25: Fiuzat M, Hamo CE, Butler J, Abraham WT, DeFilippis EM, Fonarow GC,
Lindenfeld J, Mentz RJ, Psotka MA, Solomon SD, Teerlink JR, Vaduganathan M,
Vardeny O, McMurray JJV, O'Connor CM. Optimal Background Pharmacological Therapy
for Heart Failure Patients in Clinical Trials: JACC Review Topic of the Week. J
Am Coll Cardiol. 2022 Feb 8;79(5):504-510. doi: 10.1016/j.jacc.2021.11.033.
PMID: 35115106; PMCID: PMC9180686.

26: DeFilippis EM, Blumer V, Morris AA, Cogswell R. Referring Women for Advanced
Heart Failure Therapies: Too Little, Too Late. J Card Fail. 2022
Apr;28(4):688-689. doi: 10.1016/j.cardfail.2021.12.022. Epub 2022 Jan 31. PMID:

27: DeFilippis EM, Walsh MN. Cardiovascular Outcomes of Severe Maternal
Morbidity: Decades in the Making. Circ Cardiovasc Qual Outcomes. 2022
Feb;15(2):e008727. doi: 10.1161/CIRCOUTCOMES.121.008727. Epub 2022 Jan 31. PMID:

28: Batra J, DeFilippis EM, Golob S, Clerkin K, Topkara VK, Habal MV, Restaino
S, Griffin J, Hi Lee S, Latif F, Farr MA, Sayer G, Raikelkar J, Uriel N. Impact
of Pretransplant Malignancy on Heart Transplantation Outcomes: Contemporary
United Network for Organ Sharing Analysis Amidst Evolving Cancer Therapies. Circ
Heart Fail. 2022 Apr;15(4):e008968. doi: 10.1161/CIRCHEARTFAILURE.121.008968.
Epub 2022 Jan 31. PMID: 35094567.

29: Defilippis EM, Psotka MA, Khazanie P, Cowger J, Cogswell R. Exploring
Physician Perceptions of the 2018 United States Heart Transplant Allocation
System. J Card Fail. 2022 Apr;28(4):670-674. doi:
10.1016/j.cardfail.2021.11.027. Epub 2022 Jan 14. PMID: 35039204.

30: Berman AN, DeFilippis EM, Blankstein R. Role of Income-Lifting Social
Programs in Reducing Years of Life Lost to Myocardial Infarction and Sudden
Death-Reply. JAMA Cardiol. 2022 Feb 1;7(2):230-231. doi:
10.1001/jamacardio.2021.5130. PMID: 34910076.

31: Van Spall HGC, DeFilippis EM, Lee SF, Oz UE, Perez R, Healey JS, Allen LA,
Voors AA, Ko DT, Thabane L, Connolly SJ. Sex-Specific Clinical Outcomes of the
PACT-HF Randomized Trial. Circ Heart Fail. 2021 Nov;14(11):e008548. doi:
10.1161/CIRCHEARTFAILURE.121.008548. Epub 2021 Oct 29. PMID: 34711072.

32: Rubin G, DeFilippis EM, Farr MA, Topkara VK, Yarmohammadi H. Implantable
Cardioverter-Defibrillator Use After Heart Transplantation: A Gray Area for
Primary Prevention. JACC Clin Electrophysiol. 2021 Oct;7(10):1314-1315. doi:
10.1016/j.jacep.2021.08.005. Epub 2021 Sep 29. PMID: 34600849.

33: Bhatt AS, Adler ED, Albert NM, Anyanwu A, Bhadelia N, Cooper LT, Correa A,
Defilippis EM, Joyce E, Sauer AJ, Solomon SD, Vardeny O, Yancy C, Lala A.
Coronavirus Disease-2019 and Heart Failure: A Scientific Statement From the
Heart Failure Society of America. J Card Fail. 2022 Jan;28(1):93-112. doi:
10.1016/j.cardfail.2021.08.013. Epub 2021 Sep 1. PMID: 34481067; PMCID:

34: DeFilippis EM, Solomon M, Loscalzo J. Superior Mesenteric Artery Dissection:
Classical Presentation, Novel Genetic Determinants. JACC Case Rep. 2021 Feb
24;3(4):690-693. doi: 10.1016/j.jaccas.2020.12.034. PMID: 34317605; PMCID:

35: Defilippis EM. Incorporating Cardio-Obstetrics into Advanced Heart Failure
Training. J Card Fail. 2021 Nov;27(11):1298-1299. doi:
10.1016/j.cardfail.2021.06.017. Epub 2021 Jul 15. PMID: 34274516.

36: DeFilippis EM, Van Spall HGC. Is it Time for Sex-Specific Guidelines for
Cardiovascular Disease? J Am Coll Cardiol. 2021 Jul 13;78(2):189-192. doi:
10.1016/j.jacc.2021.05.012. PMID: 34238440.

37: Golob S, Zilinyi R, Godfrey S, DeFilippis EM, Fried J, Sayer G, Blinderman
CD, Uriel N, Nakagawa S. The Prevalence of Palliative Care Consultation in
Deceased COVID-19 Patients and Its Association with End-of-Life Care. J Palliat
Med. 2022 Jan;25(1):70-74. doi: 10.1089/jpm.2021.0049. Epub 2021 Jun 30. PMID:

38: DeFilippis EM, Kirtane AJ, Axsom K. Troubleshooting CardioMEMS After
Implant-Failure to Read. JAMA Cardiol. 2021 Jun 16. doi:
10.1001/jamacardio.2021.1820. Epub ahead of print. PMID: 34132756.

39: DeFilippis EM, Henderson J, Axsom KM, Costanzo MR, Adamson PB, Miller AB,
Brett ME, Givertz MM. Remote Hemodynamic Monitoring Equally Reduces Heart
Failure Hospitalizations in Women and Men in Clinical Practice: A Sex-Specific
Analysis of the CardioMEMS Post-Approval Study. Circ Heart Fail. 2021
Jun;14(6):e007892. doi: 10.1161/CIRCHEARTFAILURE.120.007892. Epub 2021 Jun 15.
PMID: 34129363.

40: Raghu Subramanian C, Khan SU, Lone AN, Reza N, DeFilippis EM, Gulati M,
Michos ED. Representation of Women Authors in Trials of Lipid-Lowering Therapy.
J Am Heart Assoc. 2021 Jun;10(11):e020663. doi: 10.1161/JAHA.121.020663. Epub
2021 May 20. PMID: 34013740; PMCID: PMC8483514.